Fred D Finkelman Selected Research

Anaphylaxis (Anaphylactic Shock)

1/2022	Optimizing drug inhibition of IgE-mediated anaphylaxis in mice.
1/2021	Mucosal Nanoemulsion Allergy Vaccine Suppresses Alarmin Expression and Induces Bystander Suppression of Reactivity to Multiple Food Allergens.
1/2021	Suppression of IgE-mediated anaphylaxis and food allergy with monovalent anti-FcεRIα mAbs.
1/2020	Genetic inhibition of NFATC2 attenuates asparaginase hypersensitivity in mice.
1/2020	Rapid desensitization of humanized mice with anti-human FcεRIα monoclonal antibodies.
1/2020	IL-2-Agonist-Induced IFN-γ Exacerbates Systemic Anaphylaxis in Food Allergen-Sensitized Mice.
10/2018	The transcription factors GATA2 and microphthalmia-associated transcription factor regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis.
1/2018	Molecular Regulation of Histamine Synthesis.
1/2018	Anti-FcγRIIB mAb suppresses murine IgG-dependent anaphylaxis by Fc domain targeting of FcγRIII.
11/2016	IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cells.

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Fred D Finkelman Research Topics

Disease

38	Anaphylaxis (Anaphylactic Shock) 01/2022 - 04/2002
23	Hypersensitivity (Allergy) 01/2022 - 04/2003
23	Inflammation (Inflammations) 01/2019 - 12/2002
20	Asthma (Bronchial Asthma) 01/2020 - 10/2003
15	Infections 01/2018 - 04/2002
14	Food Hypersensitivity (Food Allergy) 01/2021 - 04/2008
8	Mastocytosis 12/2017 - 04/2002
8	Diarrhea 04/2016 - 12/2002
7	Shock 01/2020 - 02/2009
7	Hyperplasia 04/2011 - 02/2004
5	Eosinophilia 01/2020 - 12/2003
5	Atopic Dermatitis (Atopic Eczema) 01/2019 - 07/2006
5	Respiratory Hypersensitivity 12/2017 - 04/2005
4	Hypothermia 01/2022 - 06/2013
4	Autoimmune Diseases (Autoimmune Disease) 01/2016 - 09/2004
3	Nephritis 01/2018 - 07/2002
3	Experimental Autoimmune Myasthenia Gravis (Autoimmune Experimental Myasthenia Gravis) 01/2016 - 04/2014
3	Myasthenia Gravis 01/2016 - 04/2014
3	Immediate Hypersensitivity 03/2015 - 02/2010
3	Endotoxemia 06/2010 - 04/2008
3	Schistosomiasis (Bilharziasis) 06/2010 - 04/2008
3	Nematode Infections 01/2007 - 10/2002
2	Metaplasia 01/2020 - 12/2017
2	Leukemia 10/2019 - 01/2019
2	Pruritus (Itching) 01/2019 - 09/2012
2	Muscle Weakness 04/2015 - 04/2014
2	Peanut Hypersensitivity (Peanut Allergy) 12/2014 - 12/2010
2	Neoplasms (Cancer) 04/2010 - 12/2004
2	Hypereosinophilic Syndrome (Loeffler Endocarditis) 02/2010 - 09/2008
2	Histoplasmosis 02/2005 - 07/2003
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2020

Drug/Important Bio-Agent (IBA)

39	Immunoglobulin E (IgE)IBA 01/2022 - 04/2002
30	Interleukin-4 (Interleukin 4)IBA 01/2021 - 10/2002
29	CytokinesIBA 01/2021 - 10/2002
27	AllergensIBA 01/2022 - 10/2003
27	Immunoglobulin G (IgG)IBA 10/2019 - 04/2002
25	AntigensIBA 01/2021 - 04/2002
25	Interleukin-13IBA 01/2018 - 10/2002
12	Histamine (Histamine Dihydrochloride)FDA Link 01/2020 - 04/2002
12	OvalbuminIBA 05/2012 - 04/2002
10	AntibodiesIBA 01/2020 - 03/2005
9	Platelet Activating FactorIBA 03/2015 - 04/2002
7	anti-IgE antibodiesIBA 01/2019 - 04/2002
6	Proteins (Proteins, Gene)FDA Link 01/2018 - 05/2005
6	Peptide Hydrolases (Proteases)FDA Link 01/2018 - 08/2005
6	Interleukin-4 Receptors (Interleukin 4 Receptor)IBA 05/2012 - 03/2005
5	Complement System Proteins (Complement)IBA 01/2016 - 02/2009
5	Interleukin-9 (Interleukin 9)IBA 10/2015 - 10/2002
4	Pharmaceutical PreparationsIBA 01/2022 - 07/2003
4	IgE Receptors (Fc epsilon RI)IBA 01/2020 - 04/2003
4	Asparaginase (Elspar)FDA Link 01/2020 - 03/2015
4	Immunoglobulins (Immunoglobulin)IBA 01/2019 - 07/2004
4	Interleukin-10 (Interleukin 10)IBA 01/2016 - 02/2005
4	Peptides (Polypeptides)IBA 01/2016 - 07/2002
3	Adrenergic Agents (Adrenergic Drugs)IBA 01/2022 - 09/2007
3	Antigen-Antibody Complex (Immune Complex)IBA 10/2019 - 01/2016
3	Immunoglobulin IsotypesIBA 01/2019 - 04/2002
3	Interleukin-33IBA 01/2018 - 03/2012
3	Phosphotransferases (Kinase)IBA 01/2016 - 05/2012
3	Cholinergic ReceptorsIBA 04/2015 - 01/2007
3	Monoclonal AntibodiesIBA 12/2013 - 12/2004
3	Immunoglobulin A (IgA)IBA 05/2012 - 03/2005
3	ovalbumin-alumIBA 05/2012 - 12/2003
3	Immunoglobulin D (IgD)IBA 08/2009 - 04/2002
3	Serotonin (5 Hydroxytryptamine)IBA 09/2007 - 12/2003
3	STAT6 Transcription FactorIBA 05/2007 - 08/2006
3	InterleukinsIBA 08/2006 - 01/2004
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2022 - 09/2008
2	VaccinesIBA 01/2021 - 01/2018
2	Interleukin-2 (IL2)IBA 01/2020 - 12/2004
2	Triglycerides (Triacylglycerol)IBA 01/2018 - 02/2013
2	AutoantibodiesIBA 01/2018 - 10/2002
2	EnzymesIBA 01/2018 - 09/2007
2	muskIBA 01/2016 - 04/2014
2	Tyrosine (L-Tyrosine)FDA Link 05/2012 - 09/2007
2	ArginaseIBA 05/2012 - 06/2010
2	Messenger RNA (mRNA)IBA 03/2012 - 12/2002
2	Trefoil Factor-2IBA 03/2012 - 10/2003
2	Chemokine CCL11IBA 07/2010 - 10/2006
2	CollagenIBA 07/2010 - 04/2008
2	Interleukin-12 (IL 12)IBA 06/2010 - 07/2004
2	EpitopesIBA 07/2007 - 03/2006
2	Amino Acids FDA Link 09/2004 - 10/2002
2	Interferon-gamma (Interferon, gamma)IBA 07/2004 - 12/2002
1	Syk KinaseIBA 01/2022
1	Histamine Receptors (Histamine Receptor)IBA 01/2022
1	Adrenergic Agonists (Adrenergic Receptor Agonist)IBA 01/2022
1	Immunoglobulin Variable RegionIBA 01/2021
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2021
1	AlarminsIBA 01/2021
1	Omalizumab (Xolair)FDA Link 01/2020
1	ligelizumabIBA 01/2020
1	Biological ProductsIBA 01/2019
1	platelet activating factor receptorIBA 01/2019
1	Histamine H1 Receptors (Histamine H1 Receptor)IBA 01/2019
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 10/2018
1	Transcription Factors (Transcription Factor)IBA 10/2018

Therapy/Procedure

6	Therapeutics 01/2022 - 02/2010
3	Immunotherapy 01/2021 - 09/2004
1	Intravenous Injections 01/2020